The Nook Color is a great device, especially when CyanogenMod is installed on the device. The only issue I was having with the device, I was unable to connect to the device via ADB over USB.
I followed the steps here, but was still unable to see the device via ADB. After looking through the “fix” that was linked from XDA, I noticed that it modifies, or creates a file in %USERPROFILE%\.android\ called adb_usb.ini. That file contains vendor id’s for the devices and it contains 0x2080. As I was digging around looking to fix this issue, I noticed that in the root of my Android SDK installation there is a folder called .android. In that folder, just like the one in my user profile, there is a file called adb_usb.ini. This file is empty, except a couple comments describing the file. I added the 0x2080 to this file, then I restarted adb by doing an adb kill-server, then an adb start-server.
Now when I do adb devices, I can see the Nook Color and I can perform any adb or shell commands on the device via adb over USB.